Chromosome segmentation and investigations using generalized gradient vector flow active contours

Britto, Albert Prabhu and Ravindran, Gurubatham (2005) Chromosome segmentation and investigations using generalized gradient vector flow active contours. Online Journal of Health and Allied Sciences, 4 (2). ISSN 0972-5997

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Abstract

We investigated Generalized Gradient Vector Flow Active Contours as a suitable boundary mapping technique for Chromosome spread images which have variability in shape and size, expecting to yield a robust segmentation scheme that can be used for segmentation of similar class of images based on optimal set of parameter values. It is found experimentally that a unique set of parameter values is required for boundary mapping each chromosome image. Characterization studies have established that each parameter has an optimal range of values within which good boundary mapping results can be obtained in similar class of images. Statistical testing validates the experimental results.

EPrint Type:Article
Uncontrolled Keywords:Generalized Gradient Vector Flow, Active Contours, Deformable Curves, Chromosome, Boundary Mapping, Characterization
Subjects:Genetic Structures > Chromosomes
Diagnosis > Diagnostic Techniques and Procedures
Diagnosis > Diagnosis, Computer-Assisted
Diagnosis > Diagnostic Techniques and Procedures > Diagnostic Imaging
Genetic Structures > Chromosome Structures
-Journal Repositories > Online Journal of Health and Allied Sciences
Pathological Conditions, Signs and Symptoms > Pathologic Processes > Chromosome Aberrations
ID Code:1024
Deposited By:Dr Srinivas Kakkilaya
Deposited On:26 September 2005

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