A two-year follow up of patients with quiescent pulmonary tuberculosis following a year of chemotherapy with an intermittent (twice weekly) regimen of isoniazid plus streptomycin or a daily regimen of isoniazid plus PAS

Nazareth, O.; Devaduta, S.; Evans, C.; Fox, Wallace; Janardhanam, B.; Menon, N.K.; Radhakrishnan, S.; Ramakrishnan, C.V.; Stott, H.; Tripathy, S.P. and Velu, S. (1967) A two-year follow up of patients with quiescent pulmonary tuberculosis following a year of chemotherapy with an intermittent (twice weekly) regimen of isoniazid plus streptomycin or a daily regimen of isoniazid plus PAS. Indian Journal of Tuberculosis, 24 (2). pp. 95-103.

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Abstract

In the main analysis of a year’s study of twice-weekly high dosage isoniazid plus streptomycin (SHTW) in comparison with a standard daily regimen of isoniazid plus PAS (PH) under domiciliary conditions, 66 SHTW and 53 PH patients had attained bacteriologically quiescent disease at one year. All the patients have now been folio wed-up over a two-year period. Of these, 66 SHTW and 52 PH patients had been allocated at random to treatment in the second year with isoniazid alone or with placebo. No patient was prescribed anti-tuberculosis drugs for the third year.

EPrint Type:Article
Uncontrolled Keywords:Chemotherapy, Isoniazid, Streptomycin, PAS, Intermittent Regimen, Quiescent Pulmonary Tuberculosis, Intermittent Chemotherapy
Subjects:Therapeutics > Drug Therapy
Organic Chemicals > Hydrazines > Isoniazid
Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary
Organic Chemicals > Carboxylic Acids > Hydroxy Acids > Hydroxybenzoic Acids > Salicylic Acids > Aminosalicylic Acids > p-Aminosalicylic Acid
Carbohydrates and Hypoglycemic Agents > Carbohydrates > Glycosides > Aminoglycosides > Streptomycin
Investigative Techniques > Drug Administration Schedule
Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary
-Journal Repositories > Indian Journal of Tuberculosis
ID Code:1057
Deposited By:Mrs Naina Pandita
Deposited On:20 October 2005

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