Interpretation of the repeat tuberculin test
Narain, Raj (1968) Interpretation of the repeat tuberculin test. Indian Journal of Tuberculosis, 15 (4). pp. 147-156.
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A study with proper controls showed that a repeat tuberculin test, given at a different site, may give significantly larger reaction than the initial test in the absence of new infection. This was much more common among those with “non-specific allergy”. Mere conversion of a previous ‘negative’ reaction to a ‘positive’ one at the repeat test does not constitute evidence of new infection. Lack of realisation of this fact has quite often led to errors in the interpretation of the repeat test and estimation of the potency of a BCG vaccine.
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