A comparative clinical evaluation of the role of thioacetazone and PAS in the management of the pulmomary tuberculosis

Khanna, B.K. (1969) A comparative clinical evaluation of the role of thioacetazone and PAS in the management of the pulmomary tuberculosis. Indian Journal of Tuberculosis, 16 (2). pp. 64-68.

Full text available as:

PDF - Requires Adobe Acrobat Reader or other PDF viewer.
172 Kb


390 cases suffering from pulmonary tuberculosis admitted to Kasturba Tuberculosis Hospital were divided into four groups by random sampling. 203 cases received PAS (10 gm/day) and isoniazid (400 mgms/day), 113 received streptomycin (1 G IMI7 once a day) for first 3 months of observation in addition. 187 cases received Thioacetazone (150 mgms/ day) instead of PAS along with isoniazid (in usual dosage), 99 received streptomycin also. Our study extended over a period of six months and all along these cases were hospi- talised. It was noted that the response to thioacetazone was inferior to that of PAS particularly in those cases who had not recei- ved chemotherapy in past. Further, the tolerance to thioacetazone was found to be poorer than that of PAS.

EPrint Type:Article
Uncontrolled Keywords:PAS, Thiocetazone, Comparative Clinical Evaluation, Management, Pulmonary Tuberculosis, Investigations, Sputum, Radiological Examinations
Subjects:Fluids and Secretions > Bodily Secretions > Sputum
Organic Chemicals > Hydrazines > Isoniazid
Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary
Pharmaceutical Preparations > Drug Combinations
Organic Chemicals > Carboxylic Acids > Hydroxy Acids > Hydroxybenzoic Acids > Salicylic Acids > Aminosalicylic Acids > p-Aminosalicylic Acid
Carbohydrates and Hypoglycemic Agents > Carbohydrates > Glycosides > Aminoglycosides > Streptomycin
Investigative Techniques > Drug Administration Schedule
Organic Chemicals > Sulfur Compounds > Thiosemicarbazones
Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary
-Journal Repositories > Indian Journal of Tuberculosis
ID Code:1125
Deposited By:Mrs Naina Pandita
Deposited On:13 January 2006

Archive Staff Only: edit this record