A comparative clinical evaluation of the role of thioacetazone and PAS in the management of the pulmomary tuberculosis
Khanna, B.K. (1969) A comparative clinical evaluation of the role of thioacetazone and PAS in the management of the pulmomary tuberculosis. Indian Journal of Tuberculosis, 16 (2). pp. 64-68.
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390 cases suffering from pulmonary tuberculosis admitted to Kasturba Tuberculosis Hospital were divided into four groups by random sampling. 203 cases received PAS (10 gm/day) and isoniazid (400 mgms/day), 113 received streptomycin (1 G IMI7 once a day) for first 3 months of observation in addition. 187 cases received Thioacetazone (150 mgms/ day) instead of PAS along with isoniazid (in usual dosage), 99 received streptomycin also. Our study extended over a period of six months and all along these cases were hospi- talised. It was noted that the response to thioacetazone was inferior to that of PAS particularly in those cases who had not recei- ved chemotherapy in past. Further, the tolerance to thioacetazone was found to be poorer than that of PAS.
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