A comparative clinical evaluation of the role of thioacetazone and PAS in the management of the pulmomary tuberculosis

Khanna, B.K. (1969) A comparative clinical evaluation of the role of thioacetazone and PAS in the management of the pulmomary tuberculosis. Indian Journal of Tuberculosis, 16 (2). pp. 64-68.

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Abstract

390 cases suffering from pulmonary tuberculosis admitted to Kasturba Tuberculosis Hospital were divided into four groups by random sampling. 203 cases received PAS (10 gm/day) and isoniazid (400 mgms/day), 113 received streptomycin (1 G IMI7 once a day) for first 3 months of observation in addition. 187 cases received Thioacetazone (150 mgms/ day) instead of PAS along with isoniazid (in usual dosage), 99 received streptomycin also. Our study extended over a period of six months and all along these cases were hospi- talised. It was noted that the response to thioacetazone was inferior to that of PAS particularly in those cases who had not recei- ved chemotherapy in past. Further, the tolerance to thioacetazone was found to be poorer than that of PAS.

EPrint Type:Article
Uncontrolled Keywords:PAS, Thiocetazone, Comparative Clinical Evaluation, Management, Pulmonary Tuberculosis, Investigations, Sputum, Radiological Examinations
Subjects:Fluids and Secretions > Bodily Secretions > Sputum
Organic Chemicals > Hydrazines > Isoniazid
Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary
Pharmaceutical Preparations > Drug Combinations
Organic Chemicals > Carboxylic Acids > Hydroxy Acids > Hydroxybenzoic Acids > Salicylic Acids > Aminosalicylic Acids > p-Aminosalicylic Acid
Carbohydrates and Hypoglycemic Agents > Carbohydrates > Glycosides > Aminoglycosides > Streptomycin
Investigative Techniques > Drug Administration Schedule
Organic Chemicals > Sulfur Compounds > Thiosemicarbazones
Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary
-Journal Repositories > Indian Journal of Tuberculosis
ID Code:1125
Deposited By:Mrs Naina Pandita
Deposited On:13 January 2006

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