Some observations on atypical mycobacteria from tuberculous meningitis in children. Part 1: isolation, cultural, biochemical and biological studies
Joishy, K.N. and Sant, M.V. (1969) Some observations on atypical mycobacteria from tuberculous meningitis in children. Part 1: isolation, cultural, biochemical and biological studies. Indian Journal of Tuberculosis, 16 (4). pp. 105-117.
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About 12 strains of rapidly growing (Group IV) typical mycobacteria were isolated from a total of 100 cases of tuberculous meningitis in children, investigated. The strains were subjected to various studies such as morphological, biochemical, and biological tests with a view to identify and classify them. A comparative study with Mycobacterium tuberculosis, Mycobacterium phlei and a reference strain of Group IV (T-64) atypical mycobacteria was also carried out. It was found to be very difficult to classify these strains either with Group IV rapid grower or with saprophytic and typical mycobacteria. They formed a biological link between all these strains. The only stable characteristics exhibited by these strains are their rapid growth at 37°C and hypercatalase activity at 68°C (pH. 7.0). These are the typical characteristics of Group IV rapid growers.
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