Antidiabetic activity of Terminalia catappa Linn fruits

Nagappa, A.N.; Thakurdesai, P.A.; Venkat Rao, N and Jiwan Singh, S (2003) Antidiabetic activity of Terminalia catappa Linn fruits. Journal of Ethnopharmacology, 88. pp. 45-50. ISSN 0378-8741

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In view of alleged antidiabetic potential, effect of the petroleum ether, methanol, and aqueous extracts of Terminalia catappa Linn (combretaceae) fruit, on fasting blood sugar levels and serum biochemical analysis in alloxan-induced diabetic rats were investigated. All the three extracts of Terminalia catappa produced a significant antidiabetic activity at dose levels 1/5 of their lethal doses. Concurrent histological studies of the pancreas of these animals showed comparable regeneration by methanolic and aqueous extracts which were earlier, necrosed by alloxan.

EPrint Type:Article
Uncontrolled Keywords:Antidiabetic activity; Terminalia catappa Linn fruit; Alloxan-induced diabetes
Subjects:Complex Mixtures > Plant Preparations > Plant Extracts
Carbohydrates and Hypoglycemic Agents > Hypoglycemic Agents
Investigative Techniques > Animal Experimentation
Animals > Chordata > Vertebrates > Mammals > Rodentia > Muridae > Rats
Pharmaceutical Preparations > Plant Extracts
Endocrine Diseases > Diabetes Mellitus > Diabetes Mellitus, Experimental
Plants > Plants, Medicinal
ID Code:1275
Deposited By:Prof Anantha Naik Nagappa
Deposited On:17 January 2006

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