The advent of cytomegalovirus infection in HIV infected patients: a review

Kirubakaran, Sundar Isaac (2004) The advent of cytomegalovirus infection in HIV infected patients: a review. Online Journal of Health and Allied Sciences, 2 (4). ISSN 0972-5997

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Cytomegalovirus is considered as one among the long list of latent infections in humans that although normally controlled by the cellular immune response, gets activated after HIV infection takes its role on infecting the T4 lymphocytes. Clinical disease due to Cytomegalovirus has been recognized in up to 40% of patients with advanced HIV disease. The clinical syndromes most commonly associated include chorioretinitis, esophagitis, colitis, pneumonitis, adrenalitis and neurological disorders. Cytomegalovirus infections are usually diagnosed clinically and by serological tests for CMV immunoglobulin. Chemotherapy using systemic agents, including ganciclovir, intravenous foscarnet and intravenous cidofovir is effective. New agents, as for example an anti-sense agent against cytomegalovirus, appear promising

EPrint Type:Article
Uncontrolled Keywords:Cytomegalovirus infection, Human immunodeficiency virus, CMV colitis, CMV retinitis, AIDS
Subjects:-Journal Repositories > Online Journal of Health and Allied Sciences
Therapeutics > Drug Therapy
Immunologic Diseases > Immunologic Deficiency Syndromes > HIV Infections
Persons > Patients
Virus Diseases > Eye Infections, Viral > Cytomegalovirus Retinitis
Virus Diseases > DNA Virus Infections > Herpesviridae Infections
ID Code:1306
Deposited By:Dr Srinivas Kakkilaya
Deposited On:27 January 2006

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