The clinical spectrum of atypical mycobacteriosis
Sinclair, S. and Mittal, S.K. (1972) The clinical spectrum of atypical mycobacteriosis. Indian Journal of Tuberculosis, 19 (3). pp. 85-94.
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A total of 31 strains of atypical mycobacteria were isolated in the laboratories of the AIIMS, New Delhi from children under the age of 15 years, during the period 1966 up to Sept., 1971. Of these, clinical data is presented on 28 children : 7 presented with pulmonary tuberculosis, 5 with osteomyelitis, 4 with tuberculous meningitis, 2 with tuberculous cervical adenitis, 2 as pyrexia of unknown origin, and 1 with aortitis. The diagnosis of tuberculosis was uncertain in 2 children, while 5 had unrelated diseases, where the mycobacteria isolated were considered casual recoveries. No major distinguishing features could be attributed to tuberculosis due to atypical bacterial infection, as compared to that due to M. tuberculosis. Minor differences are discussed. The mycobacteria isolated were considered definitely pathogenic in relation to the child’s disease in 3 cases, probably pathogenic in 11 cases, possibly pathogenic in 6, probably non- pathogenic in 2, definitely non-pathogenic in 5, while in 1 case information was incomplete. The source of the isolations was: pus from discharging sinuses in 4, pus aspirated from a cervical abscess in 1, cere- brospipal fluid in 5, subdural fluid in 1, pleural fluid in 1, pharynegeal swab in 1, sputum in 2, and gastric lavage material in 13.
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