The postural tachycardia syndrome (POTS): pathophysiology, diagnosis and management

Raj, Satish R (2006) The postural tachycardia syndrome (POTS): pathophysiology, diagnosis and management. Indian Pacing and Electrophysiology Journal, 6 (2). pp. 84-99. ISSN 0972-6292

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Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia, exercise intolerance, lightheadedness, extreme fatigue, headache and mental clouding. Patients with POTS demonstrate a heart rate increase of ≥30 bpm with prolonged standing (5-30 minutes), often have high levels of upright plasma norepinephrine (reflecting sympathetic nervous system activation), and many patients have a low blood volume. POTS can be associated with a high degree of functional disability. Therapies aimed at correcting the hypovolemia and the autonomic imbalance may help relieve the severity of the symptoms. This review outlines the present understanding of the pathophysiology, diagnosis, and management of POTS.

EPrint Type:Article
Uncontrolled Keywords:Postural Tachycardia Syndrome; Pathophysiology; Diagnosis; Management
Subjects:Cardiovascular Diseases > Heart Diseases > Arrhythmia > Tachycardia
-Journal Repositories > Indian Pacing and Electrophysiology Journal
Diagnosis > Laboratory Techniques and Procedures
Pathological Conditions, Signs and Symptoms > Pathologic Processes > Arrhythmia
ID Code:1449
Deposited By:Indian Pacing and Electrophysiology Journal
Deposited On:29 March 2006

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