Toxic epidermal necrolysis (Lyell's Syndrome) due to PAS
Agnihotri, M.S. and Rastogi, S. (1972) Toxic epidermal necrolysis (Lyell's Syndrome) due to PAS. Indian Journal of Tuberculosis, 19 (4). pp. 159-160.
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A case of toxic epidermal necrolysis due to PAS toxicity was reported. Patient presented with classical trial of toxic epidermal necrolysis-prodromal toxaemia, epidermal involvementand death of epidermal cells. The initial cutaneous eruption subside by withdrawal of PAS. Again, addition of PAS resulted in acute skin toxicity and confirmed that the toxic main-festation were due to PAS. Patient tolerated Streptomycin and INH later on and was discharged, improved.
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