The role of Ziehl-Neelsen and fluroescent stains in tissue sections in the diagnosis of tuberculosis
Krishnaswami, Hemlatha and Job, C.K. (1974) The role of Ziehl-Neelsen and fluroescent stains in tissue sections in the diagnosis of tuberculosis. Indian Journal of Tuberculosis, 21 (1). pp. 18-21.
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A prospective study to detect tuberculosis was carried out on 265 consecutive lymph node biopsies over a ten month period. Histopathological evidence of tuberculosis was seen in 128 lymph nodes, while on culture pathogenic mycobacteria were isolated in 101 specimens (Krishnaswami and others, 1972). Of the 128 histologically tuberculous lymph node specimens, mycobacteria were detected in 102 speci- mens with fluorescent staining and in 91 specimens with Ziehl-Neelsen staining. While fluorescent method for demonstrating M. tuber- culosis was found to be superior to Ziehl- Neelsen technique, both are useful to confirm the diagnosis of tuberculosis where culture facilities are not available.
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