Serum levels of pyrazinamide and pyrazinoic acid following long term administraion of pyrazinamide orally
Kamal, N.; Mukerji, P.K.; Kishore, K.; Kumar, S. and Khanna, B.K. (1976) Serum levels of pyrazinamide and pyrazinoic acid following long term administraion of pyrazinamide orally. Indian Journal of Tuberculosis, 23 (1). pp. 19-25.
Full text available as:
18 volunteers and 87 proved cases of pulmonary tuberculosis were studied. The patients were getting pyrazinamide 30 mg/kg of body weight and 60 mg/kg of body weight in daily and biweekly regimen groups respectively. Serum concentration of pyrazinamide following the above mentioned dose of the drug have been studied for a period of 24 hours among volunteers. Serial serum drug concentrations were studied on initiation of treatment and at monthly interval in patients for 6 months. Serum pyrazinoic acid concentrations were simultaneously estimated in 6 volunteers and 18 patients.
Archive Staff Only: edit this record