Toxic epidermal necrolysis due to isoniazid
Mital, O.P.; Singh, R.P.; Katiyar, S.K. and Mehrotra, R.K. (1976) Toxic epidermal necrolysis due to isoniazid. Indian Journal of Tuberculosis, 23 (1). pp. 32-33.
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A young tubercular female patient developing toxic epidermal necrolysis with severe constitutional symptoms, marked vesiculobullous, eruptions all over body with peeling of skin, severe itching, otorrhoea, mild jaundice and alopecia occurring due to isoniazid is reported. It was thought to be as a manifestation of drug allergy to INH and no evidence of infective etiology could be found. The patient did not have such manifestations with any other anti-tubercular drug including PAS and streptomycin.
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