Comparision of hypersensitivity reaction to heat-concentrated and purified protein derivative in an infected herd
Singh, Gajinder; Bhaya, K.D. and Mittal, K.R. (1977) Comparision of hypersensitivity reaction to heat-concentrated and purified protein derivative in an infected herd. Indian Journal of Tuberculosis, 24 (1). pp. 22-24.
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Comparative study in 237 cattle and 18 buffaloes showed the local HCSM tuberculin to evoke milder skin reactions than PPD tuberculin. Among cattle, which formed part of an infected herd known to exhibit a high proportion of NVL reactions, none of those declared non-reacting by the British Comparative test with avian PPD tuberculin gave reaction with the heat-concentrated product so as to be considered as non-specific. The distribution of combinations of responses to mammalian and avian PPD tuberculins was suggestive of the cause of hypersensitivity in this herd being more closely related to the former.
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