Anti-microbial resistance profiles of E. coli isolated from free range chickens in urban and rural environments of Imo State, Nigeria

Okoli, Charles I (2006) Anti-microbial resistance profiles of E. coli isolated from free range chickens in urban and rural environments of Imo State, Nigeria. Online Journal of Health And Allied Sciences, 5 (1). pp. 1-11. ISSN 0972-5997

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Information on the resistance profiles of normal intestinal flora of extensively reared chickens that hardly receive antibiotics in the developing countries can serve as important means of understanding the human/animal pathogens drug resistance interactions in the zone. Three hundred and fifty E. coli isolates, comprising 133 from urban and 217 from rural sites in Imo state, Nigeria, were screened for anti-microbial resistance profile against 10 antibiotics using the disc diffusion method. Overall percentage anti-microbial resistance of the isolates against cotrimoxazole, ampicillin, nalidixic acid, chloramphenicol and nitrofurantoin (72–92%) were very high. The organisms were highly sensitive to other antibiotics, especially gentamicin and ciprofloxacin. The 59.5% overall mean percentage resistance recorded at the urban area was significantly higher than the 46.8% recorded at the rural area (p<0.05). With the exception of the figures for cotrimoxazole and ampicillin, resistance values obtained against the other antibiotics at the urban sites were statistically higher than those obtained at the rural sites (p<0.05). Zero resistance was recorded against the fluoroquinolones, norfloxacin and ciprofloxacin at all the rural sites except at Enyiogwugwu where a 28.6% resistance was obtained against norfloxacin. Since free-range chickens rarely receive antibiotic medication, it is concluded that the highly resistant E. coli organisms isolated from them may be reflecting consequences of human drug use in the study areas.

EPrint Type:Article
Uncontrolled Keywords:Anti-microbial resistance, E.coli, Free-range Chicken, Antibiotics, Nigeria
Subjects:Animal Diseases > Bird Diseases > Poultry Diseases
Bacteria > Proteobacteria
Chemical Actions and Uses > Pharmacologic Actions > Therapeutic Uses > Anti-Infective Agents > Anti-Bacterial Agents
Chemical and Pharmacologic Phenomena > Drug Resistance
Investigative Techniques > Animal Experimentation
-Journal Repositories > Online Journal of Health and Allied Sciences
Bacteria > Gram-Negative Bacteria
Geographic Locations > Africa > Africa South of the Sahara > Africa, Western > Nigeria
Bacterial Infections and Mycoses > Bacterial Infections
ID Code:1671
Deposited By:Dr Srinivas Kakkilaya
Deposited On:14 July 2006

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