Evidence-based treatment of patients with ischemic cerebrovascular disease

Anand, Ish (2002) Evidence-based treatment of patients with ischemic cerebrovascular disease. Medicine Updates. pp. 63-72.

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The results of trials that study patients with defined lesions (atrial fibrillation without valvular heart disease, various severities of carotid artery stenosis in the neck, intracranial artery stenosis) are very helpful for clinicians caring for patients with those conditions. On the other hand, trials that group all patients with brain ischemia together are not very helpful. Modern technology now makes it possible to define quickly and safely: (1) the location, nature, and severity of causative cerebrovascular, cardiac, and aortic lesions; (2> blood constituents and coagulability; and, (3) the presence, location, and severity of ischemic brain damage. As in all medicine, treatment should be aimed at the cause of disease, not the time course and severity of present damage. Clearly, more trials are needed in patients who have been studied thoroughly using modern technology. Until then, clinicians must understand the context of the trial data to determine if the results are applicable to patients sitting before them in the office or in the hospital bed.

EPrint Type:Article
Uncontrolled Keywords:Evidence Based Treatment, Patients, Ischemic Cerebrovascular Disease, Thrombolysis, Intravenous Thrombolysis, Intraarterial Thrombolysis, Anticoagulants, Heparin, Aspirin, Warfarin, Atrial Fibrillation, Dipyridamole, Ticlopidine, Clopidogrel
Subjects:Investigative Techniques > Evaluation Studies > Clinical Trials
Nervous System Diseases > Central Nervous System Diseases > Brain Diseases
Cardiovascular Diseases > Heart Diseases > Arrhythmia > Atrial Fibrillation
Organic Chemicals > Carboxylic Acids > Hydroxy Acids > Hydroxybenzoic Acids > Salicylic Acids
-Institutional Repositories > Sir Ganga Ram Hospital, New Delhi
Hematologic, Gastrointestinal, and Renal Agents > Hematologic Agents > Anticoagulants
Health Occupations > Medicine
Carbohydrates and Hypoglycemic Agents > Carbohydrates > Polysaccharides
Cardiovascular Diseases > Vascular Diseases > Embolism and Thrombosis
ID Code:1739
Deposited By:Sir Ganga Ram Hospital
Deposited On:08 August 2006

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