Effect of aspirin in the control of hyperuricemia and arthralgia due to pyrazinamide (PZA) therapy

Natraja Iyer, K. and Srinavasan, P. (1978) Effect of aspirin in the control of hyperuricemia and arthralgia due to pyrazinamide (PZA) therapy. Indian Journal of Tuberculosis, 25 (4). pp. 198-199.

Full text available as:

PDF - Requires Adobe Acrobat Reader or other PDF viewer.
108 Kb

Abstract

45 patients on Pyrazinamide therapy were studied. All of them showed an increased serum uric acid level. Thirty of them had arthralgia of varying intensity affecting one or more joints. Radiography of the involved joints showed no abnormality in any patient. On withdrawal of PZA or addition of 1.8 gm aspirin daily, uric acid level returned to normal and arthraligia disappeared in 15 days.

EPrint Type:Article
Uncontrolled Keywords:PZA, Hyperuricemia, Pyrazinamide, Serum Uric Acid, Arthralgia, Aspirin, Tuberculosis, Pulmonary Tuberculosis
Subjects:Nutritional and Metabolic Diseases > Metabolic Diseases > Hyperuricemia
Organic Chemicals > Carboxylic Acids > Hydroxy Acids > Hydroxybenzoic Acids > Salicylic Acids
Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyrazines
Hemic and Immune Systems > Blood
Musculoskeletal Diseases > Joint Diseases > Arthralgia
-Journal Repositories > Indian Journal of Tuberculosis
ID Code:1894
Deposited By:Mrs Naina Pandita
Deposited On:04 January 2007

Archive Staff Only: edit this record