Pathophysiology of breast lesion: vision beyond the clinical eye
Bhatt, Janardan; Shah, M. and Shah, F. (2002) Pathophysiology of breast lesion: vision beyond the clinical eye. Journal of Applied Basic Medical Sciences, 4 (4). pp. 81-84. ISSN ISSN ISSN 0972-4729:
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From the study, it is concluded that benign lesions of the breast are more common and occur during second decade of women' life. Malignant lesions of the breast are the second common pattern and occurring during 4th and 5th decade of women' life. Inflammatory lesions though less common, they may be curative by medical treatment. Rarely such lesions are seen in lactating mothers also. The benign lesion requires reassurance and close follow up.The prevalence of various lesions in our study was very similar to the studies done else where.Though FNAC is also routinely carried out to diagnose various lesions of breast, histopathological method is finally diagnostic. In our set up the H/R FNAC correlation was 98.75%.When our results with palpable breast lesion were compared to clinically non palpable lesions, there was no significant difference in prevalence of malignancy of breast. This suggest that it is not advisable to waif for clinically palpability of breast lesion and to withheld the screening for breast cancer .As .such palpable malignant breast lesion are associated with high morbidity and mortality. So we strongly emphasize for other methods for early detection of. breast lesion as early as possible i.e. systematic self breast examination, thermography, mammography. And when the risk is very high even MRI study also i.e. family history of cancer of breast. Histopathology is useful once the lesion is suspected.In set up , it is worth while to consider the risk factors for breast cancer.,i.e.family history, obesity, sedentary life style, high fat intake in diet, history of exposure to radiation, non lactated mothers, unmarried women, Strenious physical activity and reduction in fat intake is recommended to prevent breast cancer. AS the histology is 100% sensitive and specific tool available in all the major towns in our country.and as at present early detection and early removal of tumor is only method of curing breast cancer, mass education regarding mass screening by self breast examination, and by other tools i.e. thermography, mammography, are the mandatory measures to reduce the morbidity and mortality associated with breast cancer.
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