Association studies of cytosolic phospholipase A2 polymorphism and schizophrenia among two independent family-based samples

Kodavali, V. Chowdari; Brandstaetter, Bernard; Semwal, Prachi; Bhatia, Triptish; Deshpande, Smita; Reddy, Ravi; Wood, Jeol; Weinberg, Clarice R.; Thelma, B.K. and Nimgaonkar, Vishwajit L. (2001) Association studies of cytosolic phospholipase A2 polymorphism and schizophrenia among two independent family-based samples. Psychiatric Genetics, 11 (4). pp. 207-212.

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Abstract

An association between the cytosolic phospholipase A2 locus(cPLA2)and schizophrenia has been reported using two polymorphic DNA markers. In an attempt to replicate these results, two independent family-based samples were ascertained from the United States and India(86 and 159 families, respectively). No significant associations were detected in either sample.

EPrint Type:Article
Uncontrolled Keywords:Cytosolic Phospholipase, A2 Locus, Schizophrenia, DNA Markers, Family Based Sample
Subjects:Genetic Structures > Genes
Mental Disorders > Schizophrenia and Disorders with Psychotic Features
Enzymes and Coenzymes > Enzymes > Hydrolases
Persons > Population Groups
Investigative Techniques > Epidemiologic Methods
Immunologic and Biological Factors > Biological Factors > Biological Markers
Cells > Cellular Structures
Nucleic Acids, Nucleotides, and Nucleosides > Nucleic Acids > DNA
Genetic Phenomena > Variation (Genetics)
Environment and Public Health > Public Health > Epidemiologic Methods
ID Code:2122
Deposited By:Dr Triptish Bhatia
Deposited On:10 May 2007

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