Quinolones: drug of choice for enteric fever?
Joshi, S; Wattal, C; Sharma, A; Oberoi, JK and Prasad, KJ (2004) Quinolones: drug of choice for enteric fever? Indian Journal of Medical Microbiology, 22 (4). pp. 271-272. ISSN 0255-0857
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Enteric fever is a major public health problem in India. The emergence of multidrug-resistant Salmonella typhi (resistant to ampicillin, chloramphenicol and cotrimoxazole - ACCo) led to the use of quinolones (ciprofloxacin, ofloxacin) as the first-line drug for treatment. During the last few years, treatment failures with ciprofloxacin with increase in minimum inhibitory concentration (MIC) of S. typhi to ciprofloxacin has been observed.
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