Hyperuricemia and arthralgia during pyrazinamide therapy
Sharma, T.N.; Jain, N.K.; Mathur, B.B.; Nanavati, Virendra; Sharma, G.S. and Sharma, V.K. (1981) Hyperuricemia and arthralgia during pyrazinamide therapy. Indian Journal of Tuberculosis, 28 (2). pp. 92-96.
Full text available as:
Serum uric acid estimation was done in 189 patients who had received pyrazinamide for a duration of more than 1 month. 43-38% showed hyperuricemia and_I5.8% arthralgia. A higher incidence was found in regimen containing ethambutol and pyrazinamide. Hyperuricemia and arthralgia responded well to aspirin therapy or discontinuation of pyrazinamide. In some cases, arthralgia was self-limiting.
Archive Staff Only: edit this record