Anti-TB drug regimens: an approach through pharmacotherapeutic basis

Sen, P.K. and Chaterjee, R. (1981) Anti-TB drug regimens: an approach through pharmacotherapeutic basis. Indian Journal of Tuberculosis, 28 (3). pp. 191-199.

Full text available as:

PDF - Requires Adobe Acrobat Reader or other PDF viewer.
287 Kb

Abstract

This study introduces the pharmacological basis of choice of drugs or drugs -regimens for adequate therapeutic action. Pharmacological parameters such as peak concentration (P.C.), peak hour, half-life and minimum inhibitory concentration (MIC) coverage of Isoniazid. Thiacetazonc and Pyraziriamide were estimated. Parameters for the other four important anti-tuberculous drugs i.e. Streptomycin, Rifampicin, Ethambutol and PAS are also considered. PC/MIC ratio may be considered a better and reasonable index for evaluation of drug action. Considering al 1 these data, suggestions have been made for drugs and combination of drugs for most effective action on pharmaco-therapeutic

EPrint Type:	Article
Uncontrolled Keywords:	Anti-TB Drugs, Drug Regimens, Pulmonary Tuberculosis, Pharmacology, Isoniazid, Thiacetazone, Pyraziriamide, Streptomycin, Rifampicin, Ethambutol, PAS
Subjects:	Organic Chemicals > Hydrazines > Isoniazid Organic Chemicals > Amines > Polyamines Heterocyclic Compounds > Heterocyclic Compounds with 4 or More Rings > Rifamycins Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary Organic Chemicals > Carboxylic Acids > Hydroxy Acids > Hydroxybenzoic Acids > Salicylic Acids > Aminosalicylic Acids > p-Aminosalicylic Acid Carbohydrates and Hypoglycemic Agents > Carbohydrates > Glycosides > Aminoglycosides > Streptomycin Biological Sciences > Pharmacology Investigative Techniques > Drug Administration Schedule Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyrazines Chemical and Pharmacologic Phenomena > Drug Design Organic Chemicals > Sulfur Compounds > Thiosemicarbazones Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary -Journal Repositories > Indian Journal of Tuberculosis Health Occupations > Pharmacology
ID Code:	2295
Deposited By:	Mrs Naina Pandita
Deposited On:	26 August 2007

Archive Staff Only: edit this record