P-wave duration and dispersion in patients with peripheral edema and its amelioration

Madias, John E. (2007) P-wave duration and dispersion in patients with peripheral edema and its amelioration. Indian Pacing and Electrophysiology Journal, 7 (1). pp. 7-18. ISSN 0972-6292

Full text available as:

PDF - Requires Adobe Acrobat Reader or other PDF viewer.
578 Kb

Abstract

Background: Attenuation of the P-wave amplitudes in patients with peripheral edema (PERED) has been recently reported, with P-waves regaining some of their amplitude in patients, who subsequently experienced amelioration of their PERED. Changes in the P-waves correlated with the corresponding alterations in the QRS complexes. Also since amplitudes and durations of QRS complexes changed in parallel in patients with PERED, it was hypothesized that similar changes in the P-wave amplitudes, mean P-wave duration (P-du-mean), and P-wave dispersion (P-d), would occur in such patients. Methods: Measurements of P-wave amplitude, P-du-mean and P-d in patients who developed, or experienced alleviation, of PERED, were carried out and analyzed. Results: Although P-wave amplitudes and P-wave areas decreased with development of PERED (N = 16), and increased with its amelioration (N = 6), P-dur-mean before PERED was 66.8±14.5 ms, and at peak weight gain it was 65.2±11.9 ms, p = 0.66; also at peak weight gain and subsequent lowest weight, in the patients who lost weight, it was 66.5±9.9 ms and 72.3±12.0 ms, respectively, p = 0.38. Similarly the P-d prior to PERED was 62.3±25.2 ms, and at peak weight gain it was 74.3±29.3 ms, p = 0.09; also at peak weight and subsequent lowest weight, in the patients who lost weight, it was 58.8±34.2 ms, and 61.3±13.6 ms, respectively, p = 0.87. Conclusions: P-du-mean and P-d did not change in patients who developed PERED; their stability is attributed to the offsetting of the electrophysiologically-mediated real changes, by opposite apparent changes, imparted by PERED.

EPrint Type:Article
Uncontrolled Keywords:Electrocardiology, Electrophysiology, P-wave Duration, P-wave Dispersion, Low Voltage ECG, Peripheral Edema, Hemodialysis, Congestive Heart Failure, Amelioration
Subjects:Diagnosis > Diagnostic Techniques and Procedures > Diagnostic Techniques, Cardiovascular > Heart Function Tests > Electrocardiography
-Journal Repositories > Indian Pacing and Electrophysiology Journal
Diagnosis > Diagnostic Techniques and Procedures > Diagnostic Imaging > Ultrasonography
Diagnosis > Diagnostic Techniques and Procedures > Diagnostic Techniques, Cardiovascular > Heart Function Tests
Persons > Patients
Therapeutics > Renal Replacement Therapy
Cardiovascular Diseases > Heart Diseases > Heart Failure, Congestive
Therapeutics > Sorption Detoxification
Pathological Conditions, Signs and Symptoms > Pathologic Processes > Arrhythmia
Pathological Conditions, Signs and Symptoms > Signs and Symptoms > Edema
ID Code:2315
Deposited By:Indian Pacing and Electrophysiology Journal
Deposited On:03 March 2008

Archive Staff Only: edit this record