Chromobacterium violaceum associated with recurrent vaginal discharge among apparently healthy females in Ekpoma, Nigeria

Ezera, Agwu; Cletus, Ihongbe John; Anugboba, Okogun Godwin Ray; Chukwujekwu, Ezeonwumelu Joseph Obiezu and Osamuyime, Igbinovia (2007) Chromobacterium violaceum associated with recurrent vaginal discharge among apparently healthy females in Ekpoma, Nigeria. Online Journal of Health and Allied Sciences, 6 (1). pp. 1-10. ISSN 0972-5997

Full text available as:

PDF - Requires Adobe Acrobat Reader or other PDF viewer.
187 Kb

Abstract

Seven hundred and two high vaginal swab samples of apparently healthy adult females with recurrent vaginal discharge were collected and analyzed at Searchlight Medical Diagnostic Centre, Ekpoma between July 2003 and August 2005. Isolation, identification and antibiogram of isolates were done using standard Microbiological techniques. Randomized Block Design and Completely Randomized Design at (α = 0.1) were used to test the statistical significance of results. While occupational distribution of isolates was not statistically significant, age and response of bacterial isolates to antibiotics used were statistically significant. Total number and percentage prevalence of bacteria isolated include: 297(42.4%) Chromobacterium violaceum, 156 (22.2%) Escherichia coli and 139 (19.8%) Staphylococcus aureus. Chromobacterium violaceum was 81.8% sensitive to ofloxacin, and 12.8% to Ceftriazone. Escherichia coli and S. aureus were 70.5% and 71.9% sensitive to sparfloxacin respectively. Though source of infection of C. violaceum in Ekpoma was not very clear, soil and water contamination and other risk factors were hypothesized. A high index of suspicion is required for diagnosis. Surveillance with improved diagnostic facilities can increase awareness among health care providers on this form of infection. Appropriate systemic antimicrobial therapy to halt progression of infection is mandatory, even when the infection appears to be localized.

EPrint Type:Article
Uncontrolled Keywords:Chromobacterium violaceum, Recurrent vaginal discharge, Ekpoma, Nigeria, Escherichia coli, Staphylococcus aureus, Ofloxacin,Ceftriazone, Sparfloxacin, Drug Sensitivity
Subjects:Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Thiazoles
Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Lactams
Diagnosis > Diagnostic Techniques and Procedures
Bacteria > Proteobacteria
Bacteria > Gram-Positive Bacteria
Therapeutics > Drug Therapy
Female Genital Diseases and Pregnancy Complications > Genital Diseases, Female > Vaginal Diseases
Heterocyclic Compounds > Heterocyclic Compounds, 2-Ring > Quinolines > Quinolones > Fluoroquinolones > Ofloxacin
Immunologic Diseases > Hypersensitivity > Drug Hypersensitivity
-Journal Repositories > Online Journal of Health and Allied Sciences
Organic Chemicals > Amides > Lactams
Persons > Age Groups > Adult
Heterocyclic Compounds > Heterocyclic Compounds, 2-Ring > Quinolines > Quinolones > Fluoroquinolones
Bacteria > Gram-Negative Bacteria
Geographic Locations > Africa > Africa South of the Sahara > Africa, Western > Nigeria
ID Code:2322
Deposited By:Dr Srinivas Kakkilaya
Deposited On:19 September 2007

Archive Staff Only: edit this record