Reduction in dose requirement of vecuronium bromide during BIS guided deep hypnosis produced By sevoflurane, isoflurane and propofol

Jain, Anil Kumar (2002) Reduction in dose requirement of vecuronium bromide during BIS guided deep hypnosis produced By sevoflurane, isoflurane and propofol. 50th National Conference of Indian Society of Anaesthesiologists Coimbatore 2002.

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Abstract

Introduction: Potentiation of nondepolarizing muscle relaxants activity by volatile anesthetics usually results in either a prolongation in the duration of relaxant action or decrease in the dosage requirement of muscle relaxants. Most of the studies use 1 MAC anesthetic dose for observing effects on the action of the muscle relaxants. Deep hypnosis to blunt hemodynamic response to surgical stimulation is required in many situations. In our study decreased muscle relaxant dose requirement during BIS monitored deep hypnosis produced by Sevoflurane, Isolflurane & Propofol is studied. Material and Methods: 60 adults, 18-70 yrs. belonging to ASA 1,2 posted for laparoscopic cholestectomy, after obtaining written consent & clearance from hospital ethics committee, were included in the study. Patients were premedicated with Tab Diazepam. Beside routine monitoring of pulse, NIBP, continuous neuromuscular monitoring with TOF guard, BIS score with Aspect BIS XP monitor, ET CO2 & MAC anesthetic cone monitored with multi gas analyser (Siemens) were established.

EPrint Type:Article
Uncontrolled Keywords:Vecuronium Bromide, BIS Guided Deep Hypnosis, Sevoflurane, Isofiurane, Propofol
Subjects:Central Nervous System Agents > Hypnotics and Sedatives
Central Nervous System Agents > Central Nervous System Depressants > Anesthetics
Central Nervous System Agents > Anesthetics
-Institutional Repositories > Sir Ganga Ram Hospital, New Delhi
Organic Chemicals > Phenols > Propofol
Behavioral Disciplines and Activities > Psychotherapy
Central Nervous System Agents > Muscle Relaxants, Central
Central Nervous System Agents > Hallucinogens
Polycyclic Hydrocarbons > Steroids > Androstanes
Organic Chemicals > Ethers > Methyl Ethers
Therapeutics > Complementary Therapies
ID Code:2351
Deposited By:Sir Ganga Ram Hospital
Deposited On:28 September 2007

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