Comparative evaluation of two latex agglutination tests with whole cell agglutination test in sero-diagnosis of pulmonary tuberculosis

Sharma, T.N.; Jain, N.K.; Bareth, K.S.; Purohit, S.D.; Nanawati, V.; Madam, A. and Gupta, P.R. (1983) Comparative evaluation of two latex agglutination tests with whole cell agglutination test in sero-diagnosis of pulmonary tuberculosis. Indian Journal of Tuberculosis, 30 (1). pp. 16-19.

Full text available as:

PDF - Requires Adobe Acrobat Reader or other PDF viewer.
353 Kb

Abstract

Sera of 60 tuberculous cases, and 30 healthy controls (15 tuberculin negative. 15 tuberculin positive) were titrated against tuberculosis antigen by latex (tube and slide) and whole cell agglutination tests. Positive test results were obtained in 90% of tuberculous cases by latex slide test, 73.3 percent cases by latex tube test and in 65 % by whole cell agglutination test. Positive reactions were also obtained in 20% of tuberculin positive healthy subjects by whole cell agglutination test and in 6.6 % by the either latex agglutination tests. All the tuberculin negative subjects gave negative results by all the three methods. Percentage of positivity and mean titre values were higher in cavitary disease and increased with the extent of lesion. The latex slide test has the advantages of being simple; rapid, economic stable and well standardized and requires only a single drop of patient's serum and no technical skill. This test seems to have a role in the diagnosis of pulmonary tuberculosis.

EPrint Type:Article
Uncontrolled Keywords:Sera, Serum, Tuberculin, Tuberculosis Antigen, Latex, Whole Cell Agglutination Test, Pulmonary Tuberculosis, Diagnosis, Serologic Test
Subjects:Diagnosis > Diagnostic Techniques and Procedures
Biomedical and Dental Materials > Polymers > Latex
Immunologic and Biological Factors > Immunologic Factors > Antigens > Antigens, Bacterial > Tuberculin
Biological Phenomena, Cell Phenomena, and Immunity > Immunity
Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary
Investigative Techniques > Immunologic Techniques
Diagnosis > Diagnostic Techniques and Procedures > Skin Tests > Tuberculin Test
Hemic and Immune Systems > Blood
Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary
-Journal Repositories > Indian Journal of Tuberculosis
Diagnosis > Laboratory Techniques and Procedures
ID Code:2595
Deposited By:Mrs Naina Pandita
Deposited On:20 February 2008

Archive Staff Only: edit this record