Prolonged survival in the setting of metastatic cecal carcinoid tumor treated with combined gemcitabine-carboplatin chemotherapy regimen

Stawicki, S. Peter; Niewiarowska, Anna A. and Niewiarowski, Tomasz J. (2007) Prolonged survival in the setting of metastatic cecal carcinoid tumor treated with combined gemcitabine-carboplatin chemotherapy regimen. OPUS 12 Scientist, 1 (1). pp. 11-13. ISSN 1940-8633

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Abstract

Gastrointestinal carcinoid tumors are rare. They constitute approximately two-thirds of all carcinoid tumors. Numerous therapeutic modalities have been used to treat metastatic carcinoids, including hepatic artery embolization and chemoembolization, surgical resection, radio-frequency ablation, chemotherapy, and the use of Octreotide combined with interferon-alpha. We report a case of sustained symptomatic control in a patient with cecal carcinoid metastatic to the liver using a combination of gemcitabine and carboplatin (GC). We believe that this case illustrates the potential clinical value of the GC combination in the setting of metastatic gastrointestinal carcinoid tumor. Larger clinical trials will be required to fully elucidate the clinical efficacy and side effects of similar regimens.

EPrint Type:Article
Uncontrolled Keywords:Gastrointestinal carcinoid, Palliative care, Gemcitabine, Carboplatin, Treatment modalities, Prolonged survival, Metastatic disease
Subjects:Therapeutics > Drug Therapy
Natural Sciences > Physics > Radiation > Radiation, Nonionizing > Radio Waves
Neoplasms > Neoplasms by Histologic Type > Neoplasms, Glandular and Epithelial
Pharmaceutical Preparations > Drug Combinations
Antineoplastic and Immunosuppressive Agents > Antineoplastic Agents > Antineoplastic Combined Chemotherapy Protocols
Investigative Techniques > Drug Administration Schedule
Neoplasms > Paraneoplastic Syndromes > Neoplastic Endocrine-Like Syndromes
Neoplasms > Neoplasms by Histologic Type > Neoplasms, Nerve Tissue
Neoplasms > Neoplasms by Site > Digestive System Neoplasms
-Journal Repositories > OPUS 12 Scientist
Organic Chemicals > Organometallic Compounds > Organoplatinum Compounds
Neoplasms > Neoplasms by Histologic Type > Neoplasms, Germ Cell and Embryonal
ID Code:2597
Deposited By:Dr S. Peter Stawicki
Deposited On:21 February 2008

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