Evaluation of Elisa as a diagnostic test in pulmonary tuberculosis
Narayanan, P.R.; Acharyulu, G.S.; Krishnamurthy, P.V.; Ravoof, Abdul and Tripathy, S.P. (1983) Evaluation of Elisa as a diagnostic test in pulmonary tuberculosis. Indian Journal of Tuberculosis, 30 (1). pp. 29-32.
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The reproducibility and ability of ELISA to discriminate patients with active disease from those infested were investigated. The results obtained on 60 sputum-positive adult tuberculous patients and 60 adult control subjects showed group wise discrimination. The anti-PPD antibodies (Ig G class) were significantly elevated in tuberculous patients as compared with control subjects. But because of the large day-to-day variation and considerable overlap in the distribution of antibody levels in tuberculous and control subjects, it is not possible to use ELISA as a diagnostic tool for adult pulmonary tuberculosis
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