Undesirable effects of rifampicin alone or associated with other drugs

Daddi, G.; Lucchesi, M. and Mancini, P.A. (1983) Undesirable effects of rifampicin alone or associated with other drugs. Indian Journal of Tuberculosis, Supplement, 30 (3). pp. 32-34.

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Abstract

The side effects of Rifampicin and liver damage which it causes are rarely serious. PAS inhibits its absorption. Increase of transaminase activity is frequent but usually transient. It is a powerful enzyme-inducer. Effect of contraceptive drugs and quinidine, when simultaneously administered, is reduced and metabolism of dapsone, anti-diabetic drugs and steroids is increased.

EPrint Type:Article
Uncontrolled Keywords:Rifampicin, Mycobacterium tuberculosis, Pulmonary Tuberculosis, PAS, Quinidine, Dapsone, Live Damage
Subjects:Heterocyclic Compounds > Heterocyclic Compounds with 4 or More Rings > Rifamycins
Heterocyclic Compounds > Heterocyclic Compounds, 2-Ring > Quinolines
Heterocyclic Compounds > Alkaloids > Cinchona Alkaloids
Digestive System > Liver
Bacteria > Gram-Positive Bacteria > Actinobacteria > Actinomycetales > Mycobacteriaceae > Mycobacterium > Mycobacterium tuberculosis
Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary
Chemical and Pharmacologic Phenomena > Drug Interactions
Organic Chemicals > Sulfur Compounds > Sulfones
Heterocyclic Compounds > Heterocyclic Compounds, Bridged-Ring > Quinuclidines
Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary
-Journal Repositories > Indian Journal of Tuberculosis
ID Code:2675
Deposited By:Mrs Naina Pandita
Deposited On:05 March 2008

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