Studies on non acid fast variants of mycobacterium tuberculosis

Chandrashekar, S. (1983) Studies on non acid fast variants of mycobacterium tuberculosis. Indian Journal of Tuberculosis, Supplement, 30 (3). pp. 41-44.

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Non acid fast cell wall deficient variants of M. tuberculosis have been found in the caseous lesions of tuberculous patients. These variants can be stained by special stains. They do not grow on media used for the growth of tubercle bacilli. When injected into animals, they do not give tuberculin reactions; only granulomatous lesions are produced. They can be separated from parent forms by differential centrifugation. When injected into animals, made immune-deficient by cyclophosphatmide or Freunds adjuvant, they revert to parent form and produce tuberculosis.

EPrint Type:Article
Uncontrolled Keywords:Non acid fast cell wall deficient variants, Mycobacterium tuberculosis, Tuberculin Reactions, Tubercle bacilli, Caseous Lesions, Morphology, Growth, Culture Media, Antigenicity
Subjects:Genetic Phenomena > Phenotype
Immunologic and Biological Factors > Immunologic Factors > Antigens > Antigens, Bacterial > Tuberculin
Diagnosis > Diagnostic Techniques and Procedures > Skin Tests > Tuberculin Test
Equipment and Supplies > Culture Media
Bacteria > Gram-Positive Bacteria > Actinobacteria > Actinomycetales > Mycobacteriaceae > Mycobacterium > Mycobacterium tuberculosis
Genetic Phenomena > Genotype
Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary
Genetic Phenomena > Variation (Genetics)
Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary
-Journal Repositories > Indian Journal of Tuberculosis
ID Code:2677
Deposited By:Mrs Naina Pandita
Deposited On:05 March 2008

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