The Role of RB protein in human cancers

Garg, Abhishek D. (2007) The Role of RB protein in human cancers. Project Report. Dr. S. K. Biswas, Nagpur (M.S.), India.

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Abstract

Cancer usually owes its existence to cancer-critical genes, which are broadly classified into two main types i.e. “proto-oncogenes”, in which a gain-of-function mutation converts them to oncogenes, driving cells to become cancerous and; “tumour suppressor genes”, for which a loss-of-function mutation creates cancer. While over expression of oncogenes makes it easier to identify them, down-regulation or inactivation of tumour suppressor genes makes the job of hunting them down, tough.

EPrint Type:Monograph (Project Report)
Uncontrolled Keywords:Human, Cancer, RB Proteins, Cancer Critical Genes, Tumor Suppressor Genes, Proto-Oncogenes, Retinoblastoma, Supplementary Cancers
Subjects:Neoplasms > Neoplasms by Site > Eye Neoplasms
Genetic Structures > Genes
Amino Acids, Peptides, and Proteins > Proteins > Phosphoproteins
Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins
Amino Acids, Peptides, and Proteins > Proteins > Protein Subunits
Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins
Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins
Amino Acids, Peptides, and Proteins > Proteins > Cell Cycle Proteins
ID Code:2693
Deposited By:Mr. Abhishek Dinkarnath Garg
Deposited On:07 March 2008

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