Risk of death and recurrent ventricular arrhythmias in survivors of cardiac arrest concurrent with acute myocardial infarction

Singla, Ish; Hreybe, Haitham and Saba, Samir (2008) Risk of death and recurrent ventricular arrhythmias in survivors of cardiac arrest concurrent with acute myocardial infarction. Indian Pacing and Electrophysiology Journal, 8 (1). pp. 5-13. ISSN 5-13

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Abstract

Aims Cardiac arrest (CA) is an indication for defibrillator (ICD) implantation unless it occurs in the context of an acute myocardial infarction (AMI). We investigated the ventricular arrhythmia (VA)-free survival of patients resuscitated from CA in the setting of AMI. Methods We reviewed a database of 1600 AMI and CA survivors from which 48 patients were identified as having concurrent CA and AMI (CA+AMI group). Those patients were matched by age, gender, race, and left ventricular ejection fraction (LVEF) to 96 patients with AMI but no CA (AMI group) and 48 patients with CA but no AMI (CA group). Results Patients and controls were followed for 3.9±3.2 years. Patients in the 3 groups had similar baseline characteristics (age 63±14 yrs, 78% men, 98% white, 53% with CAD, LVEF 33±14%). The 5-year VA-free survival was 67%, 92%, and 80% for the CA+AMI, AMI, and CA groups, respectively, p<0.001. Conclusions Patients with concurrent CA and AMI are at high risk of recurrent VA, with VA-free survival rates significantly worse than those of patients with AMI but no CA, and comparable to those of patients with CA outside the context of an AMI. Accordingly, these patients should be considered for ICD implantation.

EPrint Type:Article
Uncontrolled Keywords:Cardiac Arrest, Right Ventricular Arrhythmia, Myocardial Infarction, Age, Gender, Race, ICD Plantation, Death, Risk
Subjects:-Journal Repositories > Indian Pacing and Electrophysiology Journal
Health Care Quality, Access, and Evaluation > Quality of Health Care > Health Care Evaluation Mechanisms > Statistics > Probability > Risk
Cardiovascular Diseases > Heart Diseases > Myocardial Ischemia
Cardiovascular Diseases > Heart Diseases > Heart Arrest
Cardiovascular Diseases > Heart Diseases > Arrhythmia
Pathological Conditions, Signs and Symptoms > Pathologic Processes > Death
Equipment and Supplies > Electrodes > Defibrillators > Defibrillators, Implantable
Pathological Conditions, Signs and Symptoms > Pathologic Processes > Arrhythmia
Cardiovascular Diseases > Heart Diseases > Myocardial Diseases
ID Code:2737
Deposited By:Indian Pacing and Electrophysiology Journal
Deposited On:13 March 2008

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