HIV and human co-evolution: providing potent drug targets

Garg, Abhishek D. (2006) HIV and human co-evolution: providing potent drug targets. Bioinformatics Trends, 1 (4). pp. 95-107. ISSN 0973-8037

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Abstract

HIV-AIDS has been a part of nightmares for last 25 years, since its discovery. In such a long period, research has posed no real threat to advent of this virus into human species. Incredible mutational rate of HIV has caused failure of almost all the drugs and every vaccine that the authors have devised. Recent advances in Bioinformatics tools and Data generation/mining algorithms, has facilitated in understanding evolutionary trends of HIV as well those of Humans against HIV. This has opened up new targets for drugs and vaccines to arrest the reign of HIV virus.

EPrint Type:Article
Uncontrolled Keywords:HIV, Epidemic, Virus, Retrovirus, Evolution, CCR5, Delta-32, Immune System, Phylogeny, SFV, Therapeutics, Ritonavirus
Subjects:Information Science > Data Collection
Immunologic Diseases > Hypersensitivity > Immune Complex Diseases
Hemic and Immune Systems > Immune System
Genetic Processes > Evolution
Therapeutics > Drug Therapy
Health Care Quality, Access, and Evaluation > Quality of Health Care > Health Care Evaluation Mechanisms > Data Collection
Genetic Processes > Virus Integration
Investigative Techniques > Epidemiologic Methods > Data Collection
Immunologic Diseases > Immunologic Deficiency Syndromes > HIV Infections
Immunologic and Biological Factors > Biological Products > Vaccines > Viral Vaccines
Immunologic and Biological Factors > Immunologic Factors > Virus Inhibitors
Environment and Public Health > Public Health > Epidemiologic Methods > Data Collection
Virus Diseases > RNA Virus Infections > Retroviridae Infections
ID Code:2787
Deposited By:Mr. Abhishek Dinkarnath Garg
Deposited On:02 April 2008

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