Prevalence of initial drug resistance among patients attending the clinics of Madras city

Krishnaswami, K.V.; Venkatesan, R. and Parthasarthy, R. (1984) Prevalence of initial drug resistance among patients attending the clinics of Madras city. Indian Journal of Tuberculosis, 31 (4). pp. 164-167.

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Sputum culture of 803 smear positive phases of pulmonary tuberculosis attending for the first time at the five Chest Clinics located in different parts of Madras, was positive m 750. These were further subjected to drug sensitivity tests’, 24.1% cultures were resistant to one drug, 17.6% to two drugs and 3.3% to three drugs, giving a total initial drug resistance of 45%. Total initial resistance to Isoniazid was 28.9 %, significantly higher than for any other drug. In the case of Ethambutol and Streptomycin, it was 18.7% and 17.9% respectively. Total initial resistance to Rifampicin was found to be the lowest as compared to all other drugs.

EPrint Type:Article
Uncontrolled Keywords:Sputum Culture, Sputum, Pulmonary Tuberculosis, Drug Resistance, Ethambutol, Isoniazid, Streptomycin, Rifampicin, Madras,Chest Clinic, Prevalence
Subjects:Fluids and Secretions > Bodily Secretions > Sputum
Chemical and Pharmacologic Phenomena > Drug Resistance
Organic Chemicals > Hydrazines > Isoniazid
Equipment and Supplies > Culture Media
Organic Chemicals > Amines > Polyamines
Heterocyclic Compounds > Heterocyclic Compounds with 4 or More Rings > Rifamycins
Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary
Investigative Techniques > Epidemiologic Methods > Data Collection > Vital Statistics > Morbidity > Prevalence
Investigative Techniques > Clinical Laboratory Techniques > Culture Techniques
Carbohydrates and Hypoglycemic Agents > Carbohydrates > Glycosides > Aminoglycosides > Streptomycin
Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary
-Journal Repositories > Indian Journal of Tuberculosis
ID Code:2795
Deposited By:Mrs Naina Pandita
Deposited On:08 April 2008

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