Immunological spectrum in tuberculous children
Seth, Vimlesh; Nath, Neera and Singh, Uma (1985) Immunological spectrum in tuberculous children. Indian Journal of Tuberculosis, 32 (1). pp. 29-39.
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Tuberculosis is a classic example of disease that is controlled entirely by cell mediated immunity. The latter is essentially a local phenomenon carried out by microphages that are activated locally at the site of infection by lymphokines secreted by specific subset of T. lymphocytes. The polymorphonuclear cells only engulf the bacteria but are incapable of destroying them. The immune spectrum in respect of some tuberculous manifestations has been described and need for more immunological studies in children as in adults has been brought out.
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