Multiple drug hypersensitivity in tuberculosis patient

Prvjad, C.E.; Satish Chandra, K.; Navneeth Sagar Reddy, P. and Srinivasulu, T. (1986) Multiple drug hypersensitivity in tuberculosis patient. Indian Journal of Tuberculosis, 33 (3). pp. 134-135.

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Abstract

A thirty year old female patient presented with multiple drug hypersensitivity. The clinical manifestation of the hypersensitive reaction was severe Stevens- Johnson syndrome. She was hypersensitive to isoniazid, PAS, streptomycin, procaine penicillin and, probably, thiacetazone and a herbal medicine. Although the fresh episode occurred after three weeks of therapy with isoniazid, thiaceiazone and streptomycin, the subsequent reactions manifested within short intervals. Patient tolerated ethambutol, pyrazinamide and rifampicin and completed the treatment successfully.

EPrint Type:	Article
Uncontrolled Keywords:	Multiple Drug Hypersensitivity, Pulmonary Tuberculosis, Streptomycin, PAS, Thiacetazone, Procaine, Isoniazid, Adult, Female, Ethambutol, Pyrazinamide, Rifampicin
Subjects:	Organic Chemicals > Hydrazines > Isoniazid Organic Chemicals > Carboxylic Acids > Acids, Carbocyclic Heterocyclic Compounds > Heterocyclic Compounds with 4 or More Rings > Rifamycins Pharmaceutical Preparations > Drug Combinations Organic Chemicals > Carboxylic Acids > Hydroxy Acids > Hydroxybenzoic Acids > Salicylic Acids > Aminosalicylic Acids > p-Aminosalicylic Acid Immunologic Diseases > Hypersensitivity > Drug Hypersensitivity Organic Chemicals > Sulfur Compounds > Thiosemicarbazones Heterocyclic Compounds > Heterocyclic Compounds, 2-Ring > Bicyclo Compounds, Heterocyclic Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Lactams Heterocyclic Compounds > Heterocyclic Compounds, Bridged-Ring > Bicyclo Compounds, Heterocyclic Organic Chemicals > Amines > Polyamines Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary Carbohydrates and Hypoglycemic Agents > Carbohydrates > Glycosides > Aminoglycosides > Streptomycin Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyrazines Organic Chemicals > Amides > Lactams Persons > Age Groups > Adult Chemical and Pharmacologic Phenomena > Drug Design Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary -Journal Repositories > Indian Journal of Tuberculosis
ID Code:	3015
Deposited By:	Mrs Naina Pandita
Deposited On:	27 August 2008

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