Sensitisation pattern of healthy volunteers and tuberculosis patients to various mycobacterial antigens by ELISA

Narayanan, Sujatha; Parmasivan, C.M.; Ravoof, Abdul; Narayanan, P.R. and Prabhakar, R. (1987) Sensitisation pattern of healthy volunteers and tuberculosis patients to various mycobacterial antigens by ELISA. Indian Journal of Tuberculosis, 37 (3). pp. 132-135.

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Abstract

The sensitisation pattern of 39 tuberculosis patients and 21 healthy volunteers to 9 different mycobacterial antigen sonicates was estimated using ELISA. The antibody levels of patients and volunteers were high against M. tuberculosis-7219, M. kanasii and M. scrofulaceurn and low against M. chelonei and M.fortuitum. The tuberculosis patients showed a mean antibody level which was significantly different from that of volunteers to M. tuber culosis-7219, M. kansasii, M. scrofulaceum, M. tuberculosis S.I., M. bovis and PPD-S. With respect to three antigens, namely, M. chelonei, M. fortuitum and M, avium intracellulare, there was no significant difference between patients and volunteers.

EPrint Type:Article
Uncontrolled Keywords:Mycobacteria Species, Tuberculosis Patients, ELISA, Mycobacterial Antigen, Antibody Level, M.avium, M. fortuitum. M. kanasii, M. scrofulaceurn., M.chelonei, Patients, Tuberculosis, Volunteers, Sensitiasation
Subjects:Immunologic and Biological Factors > Immunologic Factors > Antibodies
Bacterial Infections and Mycoses > Bacterial Infections > Gram-Positive Bacterial Infections > Actinomycetales Infections > Mycobacterium Infections > Tuberculosis
Immunologic and Biological Factors > Immunologic Factors > Antigens > Antigens, Bacterial
Bacterial Infections and Mycoses > Bacterial Infections > Gram-Positive Bacterial Infections > Actinomycetales Infections > Mycobacterium Infections
Investigative Techniques > Molecular Probe Techniques
Bacteria > Gram-Positive Bacteria > Actinobacteria > Actinomycetales > Mycobacteriaceae > Mycobacterium
Therapeutics > Biological Therapy > Immunotherapy > Immunization
Investigative Techniques > Immunologic Techniques
Persons > Patients
Persons > Voluntary Workers
-Journal Repositories > Indian Journal of Tuberculosis
Diagnosis > Laboratory Techniques and Procedures
ID Code:3090
Deposited By:Mrs Naina Pandita
Deposited On:26 September 2008

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