Immunological investigations in tuberculous ascites

Raji, Swamy; Archaryalu, G.S.; Balasubramaniam, Rani; Narayanan, P.R. and Prabhakar, R. (1988) Immunological investigations in tuberculous ascites. Indian Journal of Tuberculosis, 35 (1). pp. 3-7.

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Cell mediated immunity was assessed in seven patients with bacteriologically and/or histologically confirmed tuberculous ascites. Eight non-tuberculous ascites patients were included as controls. Anti-PPD antibody levels were also estimated by ELISA. Macrophage from tuberculous ascitic fluid showed increased production of'H2O2-when compared with ascitic fluid macrophages from controls. Proliferative response of lymphocytes to PPD antigen was greater in ascitic fluid than in peripheral blood in tuberculous patients, while the responses were reversed in control patients. Tuberculous ascitic fluid had higher levels of anti-PPD antibodies than ascitic fluid from controls, though their levels in peripheral blood were similar in the two groups. It is concluded that the results provide support to the concept of immunologic localization.

EPrint Type:Article
Uncontrolled Keywords:Tuberculous Ascities, Immunological Investigations, ELISA, Ascitic Fluid, Macrophages, H2O2 Assay
Subjects:Bacterial Infections and Mycoses > Bacterial Infections > Gram-Positive Bacterial Infections > Actinomycetales Infections > Mycobacterium Infections > Tuberculosis
Pathological Conditions, Signs and Symptoms > Pathologic Processes > Ascites
Fluids and Secretions > Body Fluids
Investigative Techniques > Clinical Laboratory Techniques
Cells > Connective Tissue Cells
Cells > Phagocytes
-Journal Repositories > Indian Journal of Tuberculosis
Cells > Myeloid Cells
Diagnosis > Laboratory Techniques and Procedures
ID Code:3125
Deposited By:Mrs Naina Pandita
Deposited On:30 October 2008

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