Adenosine deaminase and t-lymphocyte levels in patients with pleural effusions
Chopra, R.K.; Singh, Veena; Harbans, Lal; Saini, A.S.; Chawla, Rakesh K. and Raj, Baldev Raj (1988) Adenosine deaminase and t-lymphocyte levels in patients with pleural effusions. Indian Journal of Tuberculosis, 35 (1). pp. 22-24.
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Sixty four patients with pleural effusions (37 tuberculous, 14 malignant and 13 transudates) were studied for serum and fluid adenosine deaminase (ADA) levels and the results were compared with a group of 39 healthy controls. Serum and fluid . ADA activity was found to be significantly increased in patients with tuberculous effusions as compared to the other groups. A direct correlation between fluid and serum ADA activities was observed. In 20 patients (10 tuberculous, 6 malignant and 4transudates),T-lymphocyte counts were also made. It was observed that the percentage of fluid T-lymphocytes, in patients with tuberculous effusions, was higher than the others. The percentage of T-lymphocytes correlated well with the fluid ADA levels.
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