Serum adenosine deaminase (ADA) in differential diagnosis of pulmonary tuberculosis and no tubercular respiratory diseases

Jhamaria, J.H.; Jenaw, R.K.; Luhda, S.K.; Mathur, D.K.; Parihar, H.L. and Sharma, S.K. (1988) Serum adenosine deaminase (ADA) in differential diagnosis of pulmonary tuberculosis and no tubercular respiratory diseases. Indian Journal of Tuberculosis, 35 (1). pp. 25-27.

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Abstract

Serum adenosine deaminase (ADA) levels were determined in 20 healthy controls, 102 cases of pulmonary tuberculosis, 20 cases of suppurative lung diseases (Lung abscess and bronchiectasis 10 each) and 18 cases of malignancy lung. The mean serum levels of ADA in healthy controls were 10.09 (+2.99) units/litre, in pulmonary tuberculosis 42.47 (± 3 34), suppurative Jung diseases 26.66 (± 1.63) and in malignancy lung 24.02 (± 1.35) units/litre. The mean serum ADA levels were higher in all the three groups of patients as compared to healthy controls. The difference in mean serum levels of ADA between pulmonary tuberculosis and non-lubercular lung diseases (suppurative lung diseases & malignancy lung) was also statistically signifi-cant. Specificity (100%) and sensitivity (98%,) of this test for tuberculosis is high with a cut-off limit of 33 units/litre.

EPrint Type:Article
Uncontrolled Keywords:Serum Adenosine Deaminase, Pulmonary Tuberculosis, Lung Diseases, Patients, ADA Levels, Sputum, Lung Abscess, Bronchiectasis
Subjects:Fluids and Secretions > Bodily Secretions > Sputum
Respiratory Tract Diseases > Bronchial Diseases > Bronchiectasis
Enzymes and Coenzymes > Enzymes > Hydrolases
Respiratory Tract Diseases > Respiratory Tract Infections > Lung Abscess
Respiratory Tract Diseases > Lung Diseases
Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary
Hemic and Immune Systems > Blood
Respiratory Tract Diseases > Lung Diseases > Lung Abscess
Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary
-Journal Repositories > Indian Journal of Tuberculosis
ID Code:3130
Deposited By:Mrs Naina Pandita
Deposited On:03 November 2008

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