Hepatitis B virus among adolescents with substance use disorder: prevalence, risks, vaccinization

Yuncu, Z. (2008) Hepatitis B virus among adolescents with substance use disorder: prevalence, risks, vaccinization. Anatolian Journal of Psychiatry (Anadolu Psikiyatri Dergisi), 9 (4). pp. 208-216. ISSN 1302-6631

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Objective: Drug abuse and sexual intercourse have been reported to have equal level of effects on hepatitis B virus (HBV) contamination. Drug abuse prevalence increases in adolescence period in Turkey. The aim of presentstudy was to determine the prevalence of HBV infection and risk factors among adolescent drug users, an important health problem in our country. Methods: In the study, the medical records of the patients who were hospitalized between October 2004 and November 2007 at the inpatient service of Ege University Child and Adolescent Addiction Investigation and Practice Center (EGEBAM) were evaluated. From a total of 206 patients hospitalized within this period, 188 patients whose serological results were available, were reviewed in terms of socio-demographic features (n=188), clinical properties (n=188) and risk factors (n=41). For the comparison of categorical variables chi-square test and for the risk assessment logistic regression analysis was used. Results: All of the 188 subjects recruited in the study were male and the mean age of the sample was 16.4±1.4 years. 69.1% (n=130) of the subjects were using cannabis, 56.4% (n=106) were using inhalants, 46.8% (n=88) were using ecstasy, and 42.6% (n=80) were using alcohol. Forty-five patients (23.9%) had been exposed with the virus. Among these subjects, 14.9% (n=28) of them have been exposed to the virus via immunization while 9% of the cases have been exposed to the virus via viral infection. Anti-HBc positivity was negatively correlated with education status of the mother (p=0.005) and the father (p=0.010) and economic levels of parents (p<0.001). The number of cases with Anti-HBc positivity was found to be smaller among the patients with three or less siblings compared to the ones with 4 or more siblings. Immunization via vaccination was higher among patients with higher income (p=0.033). Discussion: The prevalence of HBV infection among adolescents with substance use disorders in our country is quite lower than other countries which might be a result of lower intravenous drug users in this age group in this country. As the prevalence of HBV infection increases with age, utmost care should be provided to avoid the spread of infection in this age group.

EPrint Type:Article
Uncontrolled Keywords:Substance Use Disorder, Adolescence, Hepatitis B Virus, Vaccination, Prevalence, Risks, Turkey
Subjects:Geographic Locations > Asia > Asia, Western > Middle East > Turkey
-Journal Repositories > Anatolian Journal of Psychiatry
Geographic Locations > Historical Geographic Locations > Middle East > Turkey
Therapeutics > Biological Therapy > Immunotherapy > Immunization > Immunotherapy, Active > Vaccination
Investigative Techniques > Epidemiologic Methods > Data Collection > Vital Statistics > Morbidity > Prevalence
Health Care Quality, Access, and Evaluation > Quality of Health Care > Health Care Evaluation Mechanisms > Statistics > Probability > Risk
Virus Diseases > Hepatitis, Viral, Human > Hepatitis B
Disorders of Environmental Origin > Substance-Related Disorders > Alcohol-Related Disorders
Mental Disorders > Substance-Related Disorders
Disorders of Environmental Origin > Substance-Related Disorders
Persons > Age Groups > Adolescent
ID Code:3157
Deposited By:Dr. Lut Tamam
Deposited On:18 November 2008

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