Corrected QT (QTc) interval in pulmonary tuberculosis
Narang, R.K.; Singh, H.G.; Ahmad, Mohd.; Shukla, R.K. and Singh, R.P. (1988) Corrected QT (QTc) interval in pulmonary tuberculosis. Indian Journal of Tuberculosis, 35 (4). pp. 195-198.
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The mean QTc interval in 30 healthy controls was 0.38S second (S.D. ± 0.024, range 0.320 to 0.430 second) while in 53 patients of pulmonary tuberculosis it was 0,413 second (S.D. +0.023, range 0.355 to 0.455 second). The difference is statistically highly significant. The QTc interval was beyond the normal range (0.436 SEC.) in 28.30% cases of pulmonary tuberculosis. It was not affected by the extent or duration of the pulmonary lesion, elevated body temperature or erythrocyte sedimentation rate. After 3 months of antituberculosis treatment there was a significant fall in QTc interval suggesting that the prolongation of QTc interval in tuberculosis was due to myocardial involvement. The exact mechanism of myocardial involvement is not clear, however; it may be duo either to direct involvement or to tuberculous toxaemia
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