Prognostic significance of circulating immune complexes in pulmonary tuberculosis

Rattan, Ashok; Gupta, Alok Deep; Maheshwari, Navneet; Prasad, Maheshwar and Bal, Ashok (1989) Prognostic significance of circulating immune complexes in pulmonary tuberculosis. Indian Journal of Tuberculosis, 36 (3). pp. 167-169.

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Abstract

Circulating immune complexes (CIC) were quantitated at initiation and after three and six monthsmonths of chemotherapy in 74 patients with smear positive pulmonary tuberculosis and in 40 age and sex matched healthy controls. At start, CIC were present in 47 (53.5%) patients and 2(5.0%) healthy controls, a significant difference. Based on clinical and radiological data, patients were classified into four groups ranging from reactives to unreactives (RR, RI, UI and UU). CIC were present in 6 out of 13 patients in the RR group, 17 out of 24 RI patients in RI group 23 out of 26 in UI group and all 11 in UU group at the initiation of therapy. After three months of chemotherapy, CIC could be detected in only 13 patients: 2, 6 and 5 in RR, RI and UI groups respectively. After 6 months of therapy, CIC could not be detected in any of the patients and all patients were also smear negative at this time.

EPrint Type:Article
Uncontrolled Keywords:Pulmonary Tuberculosis, Circulating Immune Complexes, Patients, Chemotherapy, Prognostic Significance
Subjects:Therapeutics > Drug Therapy
Diagnosis > Prognosis
Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins
Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary
Amino Acids, Peptides, and Proteins > Proteins > Globulins
Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary
Immunologic and Biological Factors > Immunologic Factors > Antigens
-Journal Repositories > Indian Journal of Tuberculosis
Immunologic and Biological Factors > Immunologic Factors > Antigen-Antibody Complex
ID Code:3265
Deposited By:Mrs Naina Pandita
Deposited On:09 June 2009

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