A study of Nigella sativa Linn. seeds for antimicrobial activity against multidrug resistant clinical strains of Pseudomonas aeruginosa

Salman, Mohd Tariq; Khan, Rahat Ali and Shukla, Indu (2009) A study of Nigella sativa Linn. seeds for antimicrobial activity against multidrug resistant clinical strains of Pseudomonas aeruginosa. Hippocratic Journal of Unani Medicine, 4 (4). pp. 95-104.

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Abstract

Nigella sativa (black cumin) seed oil and extracts were tested in varying dilutions against strains of Pseudomonas aeruginosa resistant to a number of clinically used antibiotics isolated from patients attending JN Medical College Hospital, Aligarh, using disc agar diffusion technique on inoculated Muellar Hinton agar plates under standard laboratory conditions. Both the oil and Methanolic extract showed remarkable dose dependant antibacterial activity against the tested strains upto a dilution of 1:50 as evident from the zones of inhibition. No cross resistance was noticed with any of the tested antibiotics.

EPrint Type:Article
Uncontrolled Keywords:Nigella sativa, Black seed, Pseudomonas aeruginosa, Antimicrobial Activity, Antibiotic Resistance, Black Cumin, Antibacterial Activity, Kalonji, Clinical Strains, Hospital Strains
Subjects:Therapeutics > Complementary Therapies > Medicine, Traditional
Complex Mixtures > Plant Preparations > Plant Extracts
Pharmaceutical Preparations > Plant Extracts
Biological Sciences > Pharmacology
Chemical Actions and Uses > Pharmacologic Actions > Therapeutic Uses > Anti-Infective Agents > Anti-Bacterial Agents
Bacterial Infections and Mycoses > Bacterial Infections > Gram-Negative Bacterial Infections
Chemical and Pharmacologic Phenomena > Drug Resistance
Complex Mixtures > Plant Preparations > Plant Oils
Therapeutics > Complementary Therapies > Phytotherapy
Plants > Plant Families and Groups > Angiosperms
Bacteria > Gram-Negative Bacteria > Gram-Negative Aerobic Bacteria > Gram-Negative Aerobic Rods and Cocci > Pseudomonadaceae > Pseudomonas
Plants > Plants, Medicinal
ID Code:3284
Deposited By:Dr Mohd Tariq Salman
Deposited On:22 June 2009

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