Study on pathogenicity of the Aspergillus species in experimentally immunosuppressed mice

Chhabra, D. and Dhakad, N.K. (2008) Study on pathogenicity of the Aspergillus species in experimentally immunosuppressed mice. Veterinary World, 1 (3). pp. 69-70. ISSN 0972-8988

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Abstract

Aspergillus, a saprophytic mould, distributed widely in the environment is a frequently recognized etiological agent in a number of disease conditions especially in immunocompromised patients. Mice untreated as well as immunocompromised by administering cortisone, were inoculated intraperitoneally with spores of Aspergillus spp. The administration of cortisone rendered mice highly susceptible to fatal visceral aspergillosis. Heat killed spores produced no evident lesions in control or experimental mice.

EPrint Type:Article
Uncontrolled Keywords:Aspergillus, Immunosuppression, Corticosteroid, Mice, Aspergillosis, Heat, Experiments, Cortisone
Subjects:Fungi > Mitosporic Fungi
Investigative Techniques > Animal Experimentation
Investigative Techniques > Models, Animal
Polycyclic Hydrocarbons > Steroids > Pregnanes
-Journal Repositories > Veterinary World
Immunologic and Biological Factors > Biological Factors > Virulence Factors
Animals > Chordata > Vertebrates > Mammals > Rodentia > Muridae
Animal Diseases > Disease Models, Animal
Antineoplastic and Immunosuppressive Agents > Immunosuppressive Agents
Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Adrenal Cortex Hormones
Bacterial Infections and Mycoses > Mycoses > Aspergillosis
ID Code:3314
Deposited By:Dr Anjum Sherasiya
Deposited On:19 August 2009

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