In silico identification of promiscuous MHC class-I & MHC class-II binding epitopes of rabies virus glycoprotein

Kumar, Devender (2003) In silico identification of promiscuous MHC class-I & MHC class-II binding epitopes of rabies virus glycoprotein. Project Report. Indian Veterinary Research Institute, Izatnagar, India.

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Abstract

The objectives of the study are: (i) Identification of promiscuous MHC-I & MHC-II binding epitopes of rabiesvirus glycoprotein using ProPred 1 and ProPred. (ii) Comparison of the results of the virtual matrix based methods with methods based on the support vector machines and artificial neuronal network. (iii) To look for the conserved peptides and to identify the location of the predicted promiscuous peptides in G protein.

EPrint Type:Monograph (Project Report)
Additional Information:This work is an attempt to make use of bioinformatics in the development of veterinary vaccines.Not much of the peptide-MHC binding information of Veterinary importance is available to the databases of B & T cell binding epitopes.This lack of information is hampering the proper determination of epitopes of Veterinary importnace. Anyone who is interested in depositing the info can contact me (dks0172@yahoo.com or Dr. GPS Raghava at raghava@imtech.res.in),Thanks,Devender
Uncontrolled Keywords:Immunoinformatics, In-silico, In-silico biology, Immunology, Vaccines, Veterinary Vaccines, Vaccinology, epitopes,MHC Class -I & MHC class-II
Subjects:Health Occupations > Veterinary Medicine
Investigative Techniques > Immunologic Techniques
Immunologic and Biological Factors > Biological Products > Vaccines > Viral Vaccines > Rabies Vaccines
Immunologic and Biological Factors > Biological Products > Vaccines
ID Code:332
Deposited By:Dr Devender Kumar
Deposited On:25 July 2005

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