Primary Non-Hodgkin's malignant lymphoma of the sinonasal tract

Bist, S.S.; Varshney, Saurabh; Singh, Rakesh Kumar; Bhagat, Sanjeev and Gupta, Nitin (2009) Primary Non-Hodgkin's malignant lymphoma of the sinonasal tract. Online Journal of Health and Allied Sciences, 8 (2). ISSN 0972-5997

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Abstract

Primary non-Hodgkin’s lymphomas (NHL) of the sinonasal tract are rather uncommon entities. Morphologically and radiographically, sinonasal lymphomas are difficult to distinguish from other malignant neoplasms or non- neoplastic processes. They have a variable presentation from fulminant destructive manifestations to chronic indolent type of disease and may mimic as carcinomas and invasive fungal infection respectively. We report a case of primary NHL involving sinonasal tract in elderly female, which was clinically and radiologically mimicking as sinonasal malignany and was proven as NHL on histological examination and confirmed by immunohistochemistry. A high index of suspicion, appropriate histopathological examination and immunohistochemistry is necessary to differentiate sinonasal lymphomas from other possibilities. Failure to do so may miss the diagnosis and delay appropriate treatment.

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