Relation between seizure duration, applied electrical dose and response speed to electroconvulsive therapy for patients with depression: a retrospective study

Essizoglu, A. (2009) Relation between seizure duration, applied electrical dose and response speed to electroconvulsive therapy for patients with depression: a retrospective study. Anatolian Journal of Psychiatry (Anadolu Psikiyatri Dergisi), 10 (4). pp. 286-292.

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Abstract

Objective: The aim of this study was to determine the relationship between speed of clinical response and both applied dose to produce seizure and seizure duration in inpatients with depression who underwent electroconvulsive therapy (ECT) in Dicle University Faculty of Medicine Psychiatry Service between 1st June 2006 and 1st June 2008. Methods: The sociodemodemographic and diagnostic features of 48 inpatients who underwent ECT in our clinic between 1st June 2006 and 1st June 2008 were examined retrospectively. In order to establish correlations between applied dose and seizure duration on the one hand and speed of clinical response during ECT treatment on the other, data of 21 inpatients with depression whose cure was completed in spite of adequate clinical response were analyzed using chi-square and Mann Whitney U tests. Results: In our study, 87 (16.3%) of the 533 inpatients were diagnosed with depression, 48 (9.0%) of all inpatients received ECT, 32 (66.7 %) of ECT recipients were diagnosed with depression, 21 (65.6%) of those 32 recipients had adequate clinical response and completed the cure. 57.1% of the patients with depression who completed the cure receied ECT with the indication of suicide attempt/suicidal ideation. Among patients who had adequate clinical response; our analyses indicated that patients received six and less ECT treatments needed lower dose and had longer seizure duration than patients received seven and more ECT treatment. Conclusion: The results of our study show that beginning from the first ECT treatment the droopiness of the applied dose to produce seizure and the length of seizure duration may predict that patients with depression will have more rapid clinical response during ECT treatment. However, further research which includes more patients is needed about this issue.

EPrint Type:Article
Uncontrolled Keywords:Electroconvulsive Therapy, Depression, Dose, Seizure Duration, Response Speed, Sociodemography
Subjects:Behavioral Disciplines and Activities > Psychiatric Somatic Therapies
Behavioral Disciplines and Activities > Psychological Techniques
Behavior and Behavior Mechanisms > Psychology, Social
Behavior and Behavior Mechanisms > Behavior > Behavioral Symptoms > Depression
Population Characteristics > Demography
-Journal Repositories > Anatolian Journal of Psychiatry
Nervous System Diseases > Neurologic Manifestations > Seizures
Social Sciences > Demography
ID Code:3436
Deposited By:Dr. Lut Tamam
Deposited On:09 November 2009

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