Antipsychotics and sexual dysfunction : sexual dysfunction -Part III

Mysore Nagaraj, Anil Kumar; Brahmavar Pai, Nagesh and Rao, Satheesh (2009) Antipsychotics and sexual dysfunction : sexual dysfunction -Part III. Online Journal of Health and Allied Sciences, 8 (3). ISSN 0972-5997

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Abstract

Satisfying sexual experience is an essential part of a healthy and enjoyable life for most people. Antipsychotic drugs are among the various factors that affect optimal sexual functioning. Both conventional and novel antipsychotics are associated with significant sexual side effects. This review has presented various studies comparing different antipsychotic drugs. Dopamine antagonism, increased serum prolactin, serotonergic, adrenergic and cholinergic mechanisms are all proposed to be the mechanisms for sexual dysfunction. Drug treatment for this has not given satisfactory long-term results. Knowledge of the receptor pharmacology of an individual antipsychotic will help to determine whether it is more or less likely to cause sexual side effects and its management.

EPrint Type:Article
Uncontrolled Keywords:Sexual dysfunction, Desire, Erection, Orgasm, Ejaculation, Antipsychotics
Subjects:Mental Disorders > Sexual and Gender Disorders
Female Genital Diseases and Pregnancy Complications > Genital Diseases, Female
Central Nervous System Agents > Psychotropic Drugs > Tranquilizing Agents
Central Nervous System Agents > Central Nervous System Depressants > Tranquilizing Agents
-Journal Repositories > Online Journal of Health and Allied Sciences
Central Nervous System Agents > Psychotropic Drugs
Female Genital Diseases and Pregnancy Complications > Genital Diseases, Female > Sex Disorders
Urologic and Male Genital Diseases > Genital Diseases, Male > Sex Disorders
Urologic and Male Genital Diseases > Genital Diseases, Male
ID Code:3514
Deposited By:Dr Srinivas Kakkilaya
Deposited On:06 September 2010

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