Reproductive risk factors for breast cancer: a case control study

Meshram, I.I.; Hiwarkar, P.A. and Kulkarni, P.N. (2009) Reproductive risk factors for breast cancer: a case control study. Online Journal of Health and Allied Sciences, 8 (3). ISSN 0972-5997

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Abstract

Background: Breast cancer is second most important cancer among Indian women. Although risk factors are not much prevalent as in western countries, incidence rate is increasing in India. The study was undertaken to study various risk factors associated with breast cancer. Methods: A hospital based group matched case control study was undertaken to identify risk factors. The study consisted of 105 hospitalized cases confirmed on histopathology and 210 group matched controls selected from urban field practice area, Sadar, without any malignancy. Bivariate analyses included odds ratio (OR), 95% confidence interval (CI) for odds ratio. Results: Earlier age at menarche ≤ 12 years of age, late age at first full term delivery, nulliparity, Lack of breast-feeding were found to be significantly associated with the risk of breast cancer in both pre menopausal & post menopausal women while age at menopause at or after 50 years was significantly associated with the risk in post menopausal women. Conclusions: Study suggests that the changes in menstrual and reproductive patterns among women i.e. early age at menarche and late age at first childbirth and some environmental factors in Central India may have contributed to the increase in breast cancer risk, particularly among younger women.

EPrint Type:Article
Uncontrolled Keywords:Breast Cancer, Breast Feeding, Menarche, Parity, Prevalence, Risk Factors, Childbirth
Subjects:Neoplasms > Neoplasms by Site > Breast Neoplasms
Reproductive and Urinary Physiology > Reproduction > Pregnancy > Pregnancy Outcome
Reproductive and Urinary Physiology > Reproduction
-Journal Repositories > Online Journal of Health and Allied Sciences
Reproductive and Urinary Physiology > Reproduction > Pregnancy
Endocrine Diseases > Breast Diseases > Breast Neoplasms
Health Occupations > Nutrition
Biochemical Phenomena, Metabolism, and Nutrition > Nutrition
Reproductive and Urinary Physiology > Reproduction > Menstrual Cycle
Health Care Quality, Access, and Evaluation > Quality of Health Care > Health Care Evaluation Mechanisms > Statistics > Probability > Risk > Risk Factors
ID Code:3518
Deposited By:Dr Srinivas Kakkilaya
Deposited On:09 September 2010

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